B-HOT Evidence Dashboard

Description

Each bubble represents one included study, positioned by publication year (x-axis) and study design category (y-axis). Bubble colour encodes the transplant organ: blue = Kidney, red = Heart, yellow = Other. Bubble size is proportional to sample size (N biopsies); studies with no reported N are shown as fixed-size diamonds. Hover over any bubble to see study details.

Design categories (y-axis): Multicenter · Classifier · Retrospective · Comparative · Biomarker · In silico · Mechanistic.

Description

A lollipop plot of all included studies ranked chronologically (newest first). The x-axis shows the primary sample size (N biopsies analyzed with B-HOT), with the exact number labelled next to each dot. Dot colour encodes organ: blue = Kidney, red = Heart, yellow = Other. Hover over any dot for study title, aim, and key finding.

Description

Each cell shows the count of included studies at the intersection of a transplant organ context (rows) and a study characteristic tag (columns). Colour intensity scales with count — darker green = more studies. Hover over any cell to see the individual studies it contains.

Design categories (columns): Retrospective — archival cohort analysis; Multicenter — evidence supporting transportability across sites; Classifier — work developing diagnostic models or reporting frameworks; Comparative — head-to-head comparison with another assay or method; Biomarker — biomarker discovery or validation; In silico — computational or re-analysis study; Mechanistic — investigation of immune mechanisms or pathobiology.